Working to Eradicate Gynecologic Cancers

Scientific Plenary II

Saturday, March 28, 2015: 10:25 AM-12:00 PM
International Ballroom (Hilton Chicago)
Description: This scientific plenary session will provide the first presentation of 6 original research abstracts in gynecologic cancer research. Topics to be covered include the clinical implications of global Lynch screening in endometrial cancer, associations between insurance coverage and gynecologic cancer outcomes, racial disparities in ovarian cancer outcomes, phase III trial results of vintafolide and pegylated liposomal doxorubicin in ovarian cancer, and approaches to sentinel lymph node biopsy in endometrial cancer.
Moderators:  Laura Jean Havrilesky, MD, Duke University Medical Center, Durham, NC and Noriaki Sakuragi, MD, Hokkaido University School of Medicine, Sapporo, Japan
Discussants:  Barbara A. Goff, MD, University of Washington Medical Center, Seattle, WA
10:25 AM
Introductory Remarks
L. J. Havrilesky1 and N. Sakuragi2
1Duke University Medical Center, Durham, NC, 2Hokkaido University School of Medicine, Sapporo, Japan
 
10:30 AM
6
Clinical implications for MSI, MLH1 methylation analysis and IHC in Lynch screening for endometrial cancer patients: an analysis of 940 endometrioid endometrial cancer cases from the GOG0210 study
C. C. Billingsley1, D. E. Cohn1, D. G. Mutch2, R. Broaddus3, N. Ramirez4, H. Lankes5, S. Ali6, F. J. Backes7, L. M. Landrum8, P. J. Goodfellow1, M. A. Geller9, P. A. DiSilvestro10, M. L. Pearl11, S. B. Lele6, C. C. Pritchard12 and L. A. Brinton13
1The Ohio State University, Columbus, OH, 2Washington University School of Medicine, St. Louis, MO, 3The University of Texas MD Anderson Cancer Center, Houston, TX, 4Gynecologic Oncology Group Tissue Bank, Biopathology Center, Research Institute at Nationwide Children's Hospital, Columbus, OH, 5Gynecologic Oncology Group Statistical and Data Center, Buffalo, NY, 6Roswell Park Cancer Institute, Buffalo, NY, 7The Ohio State University, James Cancer Hospital, Columbus, OH, 8The University of Oklahoma, Oklahoma City, OK, 9University of Minnesota, Minneapolis, MN, 10Women and Infants Hospital, Brown University, Providence, RI, 11Stony Brook University Hospital, St. James, NY, United States, 12University of Washington, Seattle, WA, 13Brazilian National Cancer Institute, Rockville, MD
 
10:41 AM
Distillation - Screening for Lynch Syndrome
K. H. Lu
The University of Texas MD Anderson Cancer Center, Houston, TX
 
10:47 AM
7
The association of Medicaid coverage status at the time of cancer diagnosis in women with gynecologic malignancies: a population-based study
K. M. Doll1, E. L. Barber1, K. Meng1, E. Basch1, P. A. Gehrig1, W. R. Brewster1,2 and A. M. Meyer1
1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC
 
10:58 AM
8
A randomized double-blind phase III trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD/Doxil®/Caelyx®) in combination versus PLD in participants with platinum-resistant ovarian cancer (PROCEED) (NCT01170650)
A. M. Oza1, I. B. Vergote2, L. G. Gilbert, Lucy3, P. Ghatage4, A. Lisyankaya5, S. Ghamande6, S. K. Chambers7, J. A. Arranz8, D. M. Provencher9, P. Bessette10, A. Amnon11, J. Symanowski12, R. T. Penson13, R. W. Naumann12 and R. Clark14
1Princess Margaret Hospital, Toronto, ON, Canada, 2University Hospital Leuven, Leuven, Belgium, 3McGill University, Montreal, QC, Canada, 4Tom Baker Cancer Centre, Calgary, AB, Canada, 5St. Petersburg City Oncology Hospital, Saint Petersburg, Russia, 6Georgia Regents University, Augusta, GA, 7University of Arizona Cancer Center, Tucson, AZ, 8Hospital General, Madrid, Spain, 9Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, 10University of Sherbrooke, Quebec, QC, Canada, 11Rambam Medical Center, Hafia, Israel, 12Levine Cancer Institute, Charlotte, NC, 13Massachusetts General Hospital/Harvard University, Boston, MA, 14Endocyte, Inc., Dover, DE
 
11:09 AM
9
Differences in presentation and survival of Asians versus Caucasians with ovarian cancer: a Gynecologic Oncology Group ancillary study of 7,914 patients
K. C. Fuh1, J. Java2, D. S. Kapp3, B. J. Monk4, R. A. Burger5, R. C. Young6, D. S. Alberts7, W. P. McGuire8, M. Markman9 and J. K. Chan10
1Washington University School of Medicine, St Louis, MO, 2Gynecologic Oncology Group Statistical and Data Center, Buffalo, NY, 3Stanford University, Stanford, CA, 4University of Arizona Cancer Center, Phoenix, AZ, 5University of Pennsylvania, Philadelphia, PA, 6RCY Medicine, Philadelphia, PA, 7The University of Arizona Cancer Center, Tucson, AZ, 8Inova Fairfax Hospital, Falls Church, VA, 9Cancer Treatment Centers of America, Meadowbrook, PA, 10California Pacific & Palo Alto Medical Foundation / Sutter Research Institute, San Francisco, CA
 
11:20 AM
10
Multicenter study comparing two approaches to nodal assessment in patients with low-risk endometrial carcinoma: contemporary sentinel lymph node mapping versus historical selective systematic surgical staging
A. G. Z. Eriksson1, J. A. Ducie1, N. Ali1, M. McGree2, A. L. Weaver2, G. Bogani2, B. A. Cliby2, S. C. Dowdy2, J. N. Bakkum-Gamez2, N. R. Abu-Rustum1, A. Mariani2 and M. M. Leitao1
1Memorial Sloan Kettering Cancer Center, New York, NY, 2Mayo Clinic, Rochester, MN
 
11:29 AM
11
Multicenter study assessing the detection of stage IIIC endometrial cancer in intermediate- and high-risk tumors between a contemporary sentinel node mapping vs. historical comprehensive lymphadenectomy approach
J. A. Ducie1, A. G. Z. Eriksson1, N. Ali1, M. McGree2, A. L. Weaver2, G. Bogani2, B. A. Cliby2, S. C. Dowdy2, J. N. Bakkum-Gamez2, N. R. Abu-Rustum1, A. Mariani2 and M. M. Leitao1
1Memorial Sloan Kettering Cancer Center, New York, NY, 2Mayo Clinic, Rochester, MN
 
11:35 AM
Pro and Con Debate
B. A. Goff1 and M. Ballester2
1University of Washington Medical Center, Seattle, WA, 2Hospital Universitaires Est Parisen Tenon, unknown, France
 
11:50 AM
Q&A
 
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